Polio spinal diagram. The poliovirus affects the motor neurons of the anterior horn cells, or the ventral (front) grey matter section in the spinal column, which control movement of the trunk and limb muscles including the intercostal muscles.
Scientists at the University of St Andrews have discovered new ways of studying what happens to motor neurons affected by motor neuron disease (MND) by using stem cells derived from patient skin samples, according to research published in Nature Communications.
MND is a progressive neurodegenerative condition that attacks motor neurons, specialised nerve cells in the brain and spinal cord, causing the loss of signals from the brain to muscles and eventually leading to paralysis.
Approximately 5000 people in the UK live with MND at any one time, with approximately 5 people dying of the disease every day. There is currently no cure for MND and treatment options are limited.
The joint research project led by scientists from the University of St Andrews and the University of Edinburgh has shown that even before they show any signs of damage, motor neurons affected by MND lose the ability to generate the electrical signals required to make muscles contract due to changes in specialised proteins called ion channels.
Dr Gareth Miles from the University of St Andrews and lead researcher on the project, said:
"Learning more about how and why motor neurons are lost in MND plays a crucial role in developing new treatments and ultimately finding a cure for this devastating disease. Using new developments in stem cell technology has enabled us to compare the function of motor neurons from healthy individuals with those from patients suffering from different forms of MND."
Dr Miles was supported in his research by University of St Andrews' PhD student Anna-Claire Devlin and Professor Siddharthan Chandran from the University of Edinburgh.
Dr Miles continued:
"Our findings suggest this may be an early step in understanding and ultimately treating the disease process of MND and highlights ion channels as potential targets for future therapies. Our work also demonstrates that studying the function of stem cell-derived motor neurons could be important for the development and testing of new drugs to treat and eventually cure the disease."
About motor neurone disease (MND):
- MND is a fatal, rapidly progressive disease that affects the brain and spinal cord.
- It attacks the nerves that control movement; people can still think and feel, but their muscles refuse to work.
- It can leave people locked in a failing body, unable to move, talk, and eventually, breathe.
- It affects people from all communities.
- It kills five people every day in the UK - 30% within a year and more than 50% within 2 years of diagnosis
- It has no cure.
More information: Anna-Claire Devlin, Karen Burr, Shyamanga Borooah, Joshua D. Foster, Elaine M. Cleary, Imbisaat Geti, Ludovic Vallier, Christopher E. Shaw, Siddharthan Chandran and Gareth B. Miles. "Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability." (in press)
There is a safe & effective Natural Herbal Medicine. For Total Cure Call +2349010754824, or email him drrealakhigbe@gmail.com For an Appointment with (Dr.) AKHIGBE contact him. Treatment with Natural Herbal Cure. For:Dengue Fever, Malaria. Painful or Irregular Menstruation. HIV/Aids. Diabetics. Vaginal Infections. Vaginal Discharge. Itching Of the Private Part. Breast Infection. Discharge from Breast. Breast Pain & Itching. Lower Abdominal Pain. No Periods or Periods Suddenly Stop. Women Sexual Problems. High Blood Pressure Chronic Disease. Pain during Sex inside the Pelvis. Pain during Urination. Pelvic Inflammatory Disease, (PID). Dripping Of Sperm from the Vagina As Well As for Low sperm count. Parkinson disease. Obesity, Lupus. Cancer. Tuberculosis. Zero sperm count. Bacteria, Impotence Fertility,Toxoplasmosis, Diarrhea.Herpatitis A&B, Rabies. Asthma. Quick Ejaculation. Gallstone, Cystic Fibrosis, Schizophrenia, Cirrhosis, Premature Ejaculation. Herpes. Joint Pain. Stroke. Cornelia Disease, Weak Erection. Ovarian problem, Erysipelas, Thyroid, Discharge from Penis. Bronchial Problem, HPV. Hepatitis A and B. STD. Staphylococcus + Gonorrhea + Syphilis. Heart Disease. Pile-Hemorrhoid.rheumatism, Impotence, thyroid, Autism, Sepsis Bacteria, Penis enlargement, Prostate Problem, Waist & Back Pain. Male Infertility and Female Infertility. Etc. Take Action Now. contact him & Order for your Natural Herbal Medicine: +2349010754824 and email him drrealakhigbe@gmail.com Note For an Appointment with (Dr.) AKHIGBE.I suffered in Cancer for a year and three months dieing in pain and full of heart break. One day I was searching through the internet and I came across a testimony herpes cure by doctor Akhigbe. So I contact him to try my luck, we talk and he send me the medicine through courier service and with instructions on how to be drinking it.To my greatest surprise drinking the herbal medicine within three weeks I got the changes and I was cure totally. I don't really know how it happen but there is power in Dr Akhigbe herbal medicine. He is a good herbalist doctor.
ResponderEliminarI want to share my happiness to the world on how i was cured from (HERPES VIRUS) by Dr ohunyom herbal , i visited different hospital but they gave me list of drugs like Famvir, Zovirax, and Valtrex which is very expensive to treat the symptoms, but i did not have that kind of money to buy the drugs.the one i used before did not cured me. on one faithful day, a friend of my in united kingdom told me about Dr ohunyom herbal, he told me that,it is the herbal treatment that cure is husband from hepatitis B and she told me that he have cure so many people from herpes virus with is herb medicine,then she told me to contact him that he we cure me with is herb . when i contacted Dr ohunyom, he gave me hope and say that i we be cure once i get his herbal, he send the Herbal medicine to me and i take it for two weeks and it seriously worked for me, i went to the hospital to check, my HERPES result came out negative. I am so happy as i am sharing this testimony. My advice to you all who thinks that there is no cure for herpes that is Not true, just contact him and get cure from Dr ohunyom healing herbs, he also have the herb to cure any kind of hepatitis B,C A. AND DIFFERENT KIND OF SICKNESS Remember delay in treatment leads to death.. contact Dr ohunyom on is email at (drohunyom@gmail.com) or whatsapp him on is Number :+2349060579973 and he we cure you with is HEALING HERB MEDICINE , thanks to Dr ohunyom for cure me is healing herbs medicine
ResponderEliminar